Human MACF1 Recombinant Protein (N-His) (HD829012)

Name: Human MACF1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD829012
Price: 211 USD
Availability: InStock

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100ug
1mg

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Каталожный номер	HD829012
Описание	Recombinant Human MACF1 Protein, N-His (HD829012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q9UPN3
Длина белка	Arg7114-Lys7387
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	620 kDa actin-binding protein, ABP620, ACF7, Actin cross-linking family protein 7, KIAA0465, KIAA0754, KIAA1251, MACF1, Macrophin-1, Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5, Trabeculin-alpha
Фон	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 is a ~838 kDa protein. F-actin-binding protein which plays a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics. Interaction with CAMSAP3 at the minus ends of non-centrosomal microtubules tethers microtubules minus-ends to actin filaments, regulating focal adhesion size and cell migration. 1. Kakinuma, T. et al. (2004) Experimental cell research 298, 388-98. PMID: 15265687 2. Zaoui, K. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 18517-22. PMID: 20937854 3. Ning, W. et al. (2016) Developmental cell 39, 61-74. PMID: 27693509
Примечание	For research use only

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Human MACF1 Recombinant Protein (N-His).pdf

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Formula

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Formula

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