

| Numéro de catalogue | HD984012 |
|---|---|
| Description |
Recombinant Human MAFA Protein, N-His (HD984012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q8NHW3 |
| Longueur de protéine | Arg226-Ala318 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | MAFA, Pancreatic beta-cell-specific transcriptional activator, RIPE3b1 factor, Transcription factor MafA, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A |
| Contexte | Transcription factor MafA is a ~36 kDa protein. Transcription factor that activates insulin gene expression. Acts synergistically with NEUROD1/BETA2 and PDX1. Binds the insulin enhancer C1/RIPE3b element. Binds to consensus TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequence. 1. Olbrot, M. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 6737-42. PMID: 12011435 2. Aramata, S. et al. (2005) Biochimica et biophysica acta 1730, 41-6. PMID: 15993959 3. Lu, X. et al. (2012) Biochemistry 51, 9706-17. PMID: 23148532 4. Iacovazzo, D. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, 1027-1032. PMID: 29339498 |
| Note | For research use only |
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