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Human MAFA Recombinant Protein (N-His) (HD984012)

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概要
カタログ番号HD984012
説明
Recombinant Human MAFA Protein, N-His (HD984012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
発現システムE. coli
アクセッション番号Q8NHW3
タンパク質長Arg226-Ala318
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Homo sapiens (Human)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名MAFA, Pancreatic beta-cell-specific transcriptional activator, RIPE3b1 factor, Transcription factor MafA, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A
背景

Transcription factor MafA is a ~36 kDa protein. Transcription factor that activates insulin gene expression. Acts synergistically with NEUROD1/BETA2 and PDX1. Binds the insulin enhancer C1/RIPE3b element. Binds to consensus TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequence.

1. Olbrot, M. et al. (2002) Proceedings of the National Academy of Sciences of the United States of America 99, 6737-42. PMID: 12011435
2. Aramata, S. et al. (2005) Biochimica et biophysica acta 1730, 41-6. PMID: 15993959
3. Lu, X. et al. (2012) Biochemistry 51, 9706-17. PMID: 23148532
4. Iacovazzo, D. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, 1027-1032. PMID: 29339498
注意事項 For research use only
イメージ
参考文献
Formula
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Formula
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