Human MBTPS1 Recombinant Protein (N-His) (HD222012)

Name: Human MBTPS1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD222012
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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Каталожный номер	HD222012
Описание	Recombinant Human MBTPS1 Protein, N-His (HD222012) expressed in E. coli, spanning Arg191-Pro615. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q14703
Длина белка	Arg191-Pro615
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	48.59 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	EC:3.4.21.112, Endopeptidase S1P, KIAA0091, MBTPS1, Membrane-bound transcription factor site-1 protease, S1P, SKI-1, SKI1, Subtilisin/kexin-isozyme 1
Фон	Membrane-bound transcription factor site-1 protease is a ~117 kDa protein. Serine protease that cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4: known substrates include SREBF1/SREBP1, SREBF2/SREBP2, BDNF, GNPTAB, ATF6, ATF6B and FAM20C. Cleaves substrates after Arg-Ser-Val-Leu (SREBP2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2. Also mediates the first step in the proteolytic activation of the cyclic AMP-dependent transcription factor ATF-6 (ATF6 and ATF6B). Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes. 1. Touré, BB. et al. (2000) The Journal of biological chemistry 275, 2349-58. PMID: 10644685 2. Okada, T. et al. (2003) The Journal of biological chemistry 278, 31024-32. PMID: 12782636 3. Marschner, K. et al. (2011) Science (New York, N.Y.) 333, 87-90. PMID: 21719679 4. Chen, X. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 34349020 7. Murakami, T. et al. (2006) Journal of neurochemistry 96, 1090-100. PMID: 16417584
Примечание	For research use only

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Human MBTPS1 Recombinant Protein (N-His).pdf

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Formula

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