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| カタログ番号 | HD501012 |
|---|---|
| 説明 |
Recombinant Human MIEF1 Protein, N-GST & C-His (HD501012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | L0R8F8 |
| タンパク質長 | Ala2-Ile70 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | AltMIEF1, AltMiD51, Alternative MIEF1 protein, MIEF1, MIEF1 microprotein, MIEF1-MP, Mitochondrial ribosome and complex I assembly factor AltMIEF1, alternative transcript upstream of MiD51 |
| 背景 | Mitochondrial ribosome and complex I assembly factor AltMIEF1 is a ~8 kDa protein. Assembly factor involved in the biogenesis of the mitochondrial-specific ribosomes (mitoribosomes). Specifically associates with intermediates of the mitochondrial ribosome large subunit (mt-LSU) and is required for proper ribosome assembly, possibly preventing premature association of the large and small ribosomal subunits. Thereby, indirectly regulates mitochondrial translation. It is also required for complete assembly of the mitochondrial respiratory chain complex I. May also function in DNM1L-mediated mitochondrial fission. 1. Brown, A. et al. (2017) Nature structural & molecular biology 24, 866-869. PMID: 28892042 2. Rathore, A. et al. (2018) Biochemistry 57, 5564-5575. PMID: 30215512 3. Dibley, MG. et al. (2020) Molecular & cellular proteomics : MCP 19, 65-77. PMID: 31666358 |
| 注意事項 | For research use only |
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