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| カタログ番号 | HP852022 |
|---|---|
| 説明 |
Recombinant Human MOSPD2 Protein, N-His (HP852022) expressed in E. coli, spanning Met1-Thr251. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q8NHP6 |
| タンパク質長 | Met1-Thr251 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 32.20 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | MOSPD2, Motile sperm domain-containing protein 2 |
| 背景 | Motile sperm domain-containing protein 2 is a ~59 kDa protein. Endoplasmic reticulum-anchored protein that mediates the formation of contact sites between the endoplasmic (ER) and endosomes, mitochondria or Golgi through interaction with conventional- and phosphorylated-FFAT-containing organelle-bound proteins. In addition, forms endoplasmic reticulum (ER)-lipid droplets (LDs) contacts through a direct protein-membrane interaction and participates in LDs homeostasis. The attachment mechanism involves an amphipathic helix that has an affinity for lipid packing defects present at the surface of LDs. Promotes migration of primary monocytes and neutrophils, in response to various chemokines. 1. Di Mattia, T. et al. (2018) EMBO reports 19. PMID: 29858488 2. Di Mattia, T. et al. (2020) The EMBO journal 39, e104369. PMID: 33124732 3. Zouiouich, M. et al. (2022) The Journal of cell biology 221. PMID: 35389430 4. Mendel, I. et al. (2017) Journal of immunology (Baltimore, Md. : 1950) 198, 2125-2132. PMID: 28137892 |
| 注意事項 | For research use only |
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