Human/Mouse/Rat GABRA1 Recombinant Protein (N-His) (HB280012)

Name: Human/Mouse/Rat GABRA1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HB280012
Price: 211 USD
Availability: InStock

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1mg

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Каталожный номер	HB280012
Описание	Recombinant Human BABRA1 Protein, N-His (HB280012) expressed in E. coli, spanning Arg64-Lys249. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	P14867, P62812, P62813
Длина белка	Arg64-Lys249
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	23.77 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	GABA(A) receptor subunit alpha-1, GABAAR subunit alpha-1, GABRA1, Gamma-aminobutyric acid receptor subunit alpha-1
Фон	Gamma-aminobutyric acid receptor subunit alpha-1 is a ~51 kDa protein. Alpha subunit of the heteropentameric ligand-gated chloride channel gated by Gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain. GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit interface(s). When activated by GABA, GABAARs selectively allow the flow of chloride anions across the cell membrane down their electrochemical gradient. Alpha-1/GABRA1-containing GABAARs are largely synaptic. Chloride influx into the postsynaptic neuron following GABAAR opening decreases the neuron ability to generate a new action potential, thereby reducing nerve transmission. 1. Fuchs, C. et al. (2013) The European journal of neuroscience 38, 3146-58. PMID: 23909897 2. Brown, LE. et al. (2014) Journal of visualized experiments : JoVE, e52115. PMID: 25489750 3. Zhu, S. et al. (2018) Nature 559, 67-72. PMID: 29950725 4. Laverty, D. et al. (2019) Nature 565, 516-520. PMID: 30602789
Примечание	For research use only

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Human/Mouse/Rat GABRA1 Recombinant Protein (N-His).pdf

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