

| Каталожный номер | HA280011 |
|---|---|
| Описание |
Recombinant Human MXRA8 Protein, C-His (HA280011) expressed in Mammalian Cells, spanning His23-Gln341. Purity: >90% by SDS-PAGE.
Highlights
|
| Система экспрессии | Mammalian cells |
| Номер доступа | Q9BRK3 |
| Длина белка | His23-Gln341 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Прогнозируемая молекулярная масса | 38.18 kDa |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | Limitrin, MXRA8, Matrix remodeling-associated protein 8 |
| Фон | Matrix remodeling-associated protein 8 is a ~49 kDa protein. Transmembrane protein which can modulate activity of various signaling pathways, probably via binding to integrin ITGAV:ITGB3. Mediates heterophilic cell-cell interactions in vitro. Inhibits osteoclastogenesis downstream of TNFSF11/RANKL and CSF1, where it may function by attenuating signaling via integrin ITGB3 and MAP kinase p38. Plays a role in cartilage formation where it promotes proliferation and maturation of growth plate chondrocytes. Stimulates formation of primary cilia in chondrocytes. 1. Jung, YK. et al. (2012) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 27, 2024-34. PMID: 22492581 2. Han, SW. et al. (2013) Cardiovascular research 98, 73-82. PMID: 23386276 |
| Примечание | For research use only |



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