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| カタログ番号 | HD795012 |
|---|---|
| 説明 |
Recombinant Human NDST2 Protein, N-His (HD795012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | P52849 |
| タンパク質長 | Ser41-Glu597 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2, EC:2.8.2.-, EC:2.8.2.8, EC:3.-.-.-, Glucosaminyl N-deacetylase/N-sulfotransferase 2, HSST2, Heparan sulfate N-deacetylase 2, Heparan sulfate N-sulfotransferase 2, N-HSST 2, N-heparan sulfate sulfotransferase 2, NDST-2, NDST2 |
| 背景 | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 is a ~100 kDa protein. Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Required for the exosomal release of SDCBP, CD63 and syndecan. 1. Baietti, MF. et al. (2012) Nature cell biology 14, 677-85. PMID: 22660413 |
| 注意事項 | For research use only |
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