Human Nectin-4 Recombinant Protein (C-Fc) (HV985021)

Name: Human Nectin-4 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: HV985021
Price: 298 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo	HV985021
Descripción	Recombinant Human NECTIN4/PVRL4 Protein, C-Fc (HV985021) expressed in Mammalian Cells, spanning Met1-Ser349. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	Mammalian cells
Número de acceso	Q96NY8
Longitud de proteína	Met1-Ser349
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Peso molecular predicho	63.02 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. RECONSTITUTION PROTOCOL 1. Allow the product to be reconstituted and the reconstitution diluent to reach room temperature. 2. Tap or briefly centrifuge the product vial before opening to dislodge any lyophilized material that may be dispersed on the wall or cap of the vial. 3. Use the diluent and stock concentration recommended in the product datasheet. If preparing a stock concentration higher than recommended, contact Technical Service. 4. After adding the diluent, re-cap the vial and invert gently by hand or place on a slow rocking platform to allow the reconstitution diluent to coat all the surfaces inside the vial. Note: Do not mix by vortexing or by pipetting the material up and down. 5. Allow the vial to sit at room temperature with gentle agitation for at least 15 minutes before aliquotting or using. 6. Store the reconstituted material in single use aliquots in polypropylene or siliconized tubes. Aliquots of 10 μL or larger are recommended.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	Nectin-4, Ig superfamily receptor LNIR, Nectin cell adhesion molecule 4, Poliovirus receptor-related protein 4, Processed poliovirus receptor-related protein 4, NECTIN4, LNIR, PRR4, PVRL4
Fondo	Nectin-4 (NECTIN4/PVRL4) is a ~55 kDa protein. Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. NECTIN4 is the therapeutic target of enfortumab vedotin (Padcev).
Nota	For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Recombinant Human NECTIN4/PVRL4 Protein, C-Fc
Bioactivity

Immobilized HV985021 Human NECTIN4/PVRL4 Recombinant Protein (C-Fc) at 2 μg/mL(100 μL/well) can bind HS747011 Human CD111/NECTIN1 Recombinant Protein (C-His), the EC 50 is 13.4 μg/mL.
Bioactivity

Immobilized HV985021 Human NECTIN4/PVRL4 Recombinant Protein (C-Fc) at 2 μg/mL(100 μL/well) can bind HS747021 Human CD111/NECTIN1 Recombinant Protein (C-Fc), the EC 50 is 954 ng/mL.