

| Numéro de catalogue | HC156012 |
|---|---|
| Description |
Recombinant Human NLRC4 Protein, N-His (HC156012) expressed in E. coli, spanning Asn764-Phe1019. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q9NPP4 |
| Longueur de protéine | Asn764-Phe1019 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 31.16 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | CARD, LRR, and NACHT-containing protein, CARD12, CED-4-like protein Clan, CLAN, CLAN1, Caspase recruitment domain-containing protein 12, IPAF, Ice protease-activating factor, Ipaf, NLR family CARD domain-containing protein 4, NLRC4 |
| Contexte | NLR family CARD domain-containing protein 4 is a ~116 kDa protein. Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis. The NLRC4 inflammasome is activated as part of the innate immune response to a range of intracellular bacteria. 1. Damiano, JS. et al. (2004) The Biochemical journal 381, 213-9. PMID: 15107016 |
| Note | For research use only |
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