Human NPLOC4 Recombinant Protein (N-His) (HE005012)

Name: Human NPLOC4 Recombinant Protein (N-His)
Brand: abinScience
SKU: HE005012
Price: 211 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HE005012
Description	Recombinant Human NPLOC4 Protein, N-His (HE005012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	Q8TAT6
Longueur de protéine	Arg221-Thr608
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	KIAA1499, NPL4, NPLOC4, Nuclear protein localization protein 4 homolog, Protein NPL4
Contexte	Nuclear protein localization protein 4 homolog is a ~68 kDa protein. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. Acts as a negative regulator of type I interferon production via the complex formed with VCP and UFD1, which binds to RIGI and recruits RNF125 to promote ubiquitination and degradation of RIGI. 1. Hao, Q. et al. (2015) The EMBO journal 34, 2903-20. PMID: 26471729
Note	For research use only

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Human NPLOC4 Recombinant Protein (N-His).pdf

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