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| カタログ番号 | HD064012 |
|---|---|
| 説明 |
Recombinant Human NR0B1 Protein, N-His (HD064012) expressed in E. coli, spanning Leu128-Ile470. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | P51843 |
| タンパク質長 | Leu128-Ile470 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 40.67 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | AHC, DAX1, DSS-AHC critical region on the X chromosome protein 1, NR0B1, Nuclear receptor DAX-1, Nuclear receptor subfamily 0 group B member 1 |
| 背景 | Nuclear receptor subfamily 0 group B member 1 is a ~51 kDa protein. Nuclear receptor that lacks a DNA-binding domain and acts as a corepressor that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency. 1. Suzuki, T. et al. (2003) Molecular and cellular biology 23, 238-49. PMID: 12482977 2. Seacrist, CD. et al. (2020) Structure (London, England : 1993) 28, 830-846.e9. PMID: 32433991 3. Zanaria, E. et al. (1994) Nature 372, 635-41. PMID: 7990953 4. Guo, W. et al. (1996) The Journal of clinical endocrinology and metabolism 81, 2481-6. PMID: 8675564 |
| 注意事項 | For research use only |
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