Human NR4A1 Recombinant Protein (N-His) (HD945012)

Name: Human NR4A1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD945012
Price: 211 USD
Availability: InStock

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100ug
1mg

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Vista general

Número de catálogo	HD945012
Descripción	Recombinant Human NR4A1 Protein, N-His (HD945012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P22736
Longitud de proteína	Lys397-Phe598
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	Early response protein NAK1, GFRP1, HMR, NAK1, NR4A1, Nuclear hormone receptor NUR/77, Nuclear receptor subfamily 4immunitygroup A member 1, Nur77, Orphan nuclear receptor HMR, Orphan nuclear receptor TR3, ST-59, Testicular receptor 3
Fondo	Nuclear receptor subfamily 4immunitygroup A member 1 is a ~64 kDa protein. Orphan nuclear receptor. Binds the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Binds 9-cis-retinoic acid outside of its ligand-binding (NR LBD) domain. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Regulates the inflammatory response in macrophages by regulating metabolic adaptations during inflammation, including repressing the transcription of genes involved in the citric acid cycle (TCA). 1. Zhan, Y. et al. (2008) Nature chemical biology 4, 548-56. PMID: 18690216 2. Woronicz, JD. et al. (1994) Nature 367, 277-81. PMID: 8121493 3. Philips, A. et al. (1997) Molecular and cellular biology 17, 5946-51. PMID: 9315652 4. Zhan, YY. et al. (2012) Nature chemical biology 8, 897-904. PMID: 22983157 5. Harant, H. et al. (2004) Nucleic acids research 32, 5280-90. PMID: 15466594
Nota	For research use only

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Referencias

Datasheet

Human NR4A1 Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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