Human NR4A1 Recombinant Protein (N-His) (HD945012)

Name: Human NR4A1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD945012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HD945012
Description	Recombinant Human NR4A1 Protein, N-His (HD945012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	P22736
Longueur de protéine	Lys397-Phe598
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	Early response protein NAK1, GFRP1, HMR, NAK1, NR4A1, Nuclear hormone receptor NUR/77, Nuclear receptor subfamily 4immunitygroup A member 1, Nur77, Orphan nuclear receptor HMR, Orphan nuclear receptor TR3, ST-59, Testicular receptor 3
Contexte	Nuclear receptor subfamily 4immunitygroup A member 1 is a ~64 kDa protein. Orphan nuclear receptor. Binds the NGFI-B response element (NBRE) 5'-AAAGGTCA-3'. Binds 9-cis-retinoic acid outside of its ligand-binding (NR LBD) domain. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Regulates the inflammatory response in macrophages by regulating metabolic adaptations during inflammation, including repressing the transcription of genes involved in the citric acid cycle (TCA). 1. Zhan, Y. et al. (2008) Nature chemical biology 4, 548-56. PMID: 18690216 2. Woronicz, JD. et al. (1994) Nature 367, 277-81. PMID: 8121493 3. Philips, A. et al. (1997) Molecular and cellular biology 17, 5946-51. PMID: 9315652 4. Zhan, YY. et al. (2012) Nature chemical biology 8, 897-904. PMID: 22983157 5. Harant, H. et al. (2004) Nucleic acids research 32, 5280-90. PMID: 15466594
Note	For research use only

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Human NR4A1 Recombinant Protein (N-His).pdf

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