Human NR4A3 Recombinant Protein (N-His) (HD896012)

Name: Human NR4A3 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD896012
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HD896012
Description	Recombinant Human NR4A3 Protein, N-His (HD896012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	Q92570
Longueur de protéine	Ile396-Phe626
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	CHN, CSMF, MINOR, Mitogen-induced nuclear orphan receptor, NOR1, NR4A3, Neuron-derived orphan receptor 1, Nuclear hormone receptor NOR-1, Nuclear receptor subfamily 4 group A member 3, TEC, Translocated in extraskeletal chondrosarcoma
Contexte	Nuclear receptor subfamily 4 group A member 3 is a ~68 kDa protein. Transcriptional activator that binds to regulatory elements in promoter regions in a cell- and response element (target)-specific manner. Induces gene expression by binding as monomers to the NR4A1 response element (NBRE) 5'-AAAAGGTCA-3' site and as homodimers to the Nur response element (NurRE) site in the promoter of their regulated target genes. Plays a role in the regulation of proliferation, survival and differentiation of many different cell types and also in metabolism and inflammation. Mediates proliferation of vascular smooth muscle, myeloid progenitor cell and type B pancreatic cells; promotes mitogen-induced vascular smooth muscle cell proliferation through transactivation of SKP2 promoter by binding a NBRE site. Upon PDGF stimulation, stimulates vascular smooth muscle cell proliferation by regulating CCND1 and CCND2 expression. 1. Zhao, Y. et al. (2010) Circulation research 107, 501-11. PMID: 20558821 2. Liu, Q. et al. (2013) American journal of physiology. Endocrinology and metabolism 305, E1081-92. PMID: 24022864
Note	For research use only

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Human NR4A3 Recombinant Protein (N-His).pdf

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