Human NR4A3 Recombinant Protein (N-His) (HD896012)

Name: Human NR4A3 Recombinant Protein (N-His)
Brand: abinScience
SKU: HD896012
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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Обзор

Каталожный номер	HD896012
Описание	Recombinant Human NR4A3 Protein, N-His (HD896012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q92570
Длина белка	Ile396-Phe626
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	CHN, CSMF, MINOR, Mitogen-induced nuclear orphan receptor, NOR1, NR4A3, Neuron-derived orphan receptor 1, Nuclear hormone receptor NOR-1, Nuclear receptor subfamily 4 group A member 3, TEC, Translocated in extraskeletal chondrosarcoma
Фон	Nuclear receptor subfamily 4 group A member 3 is a ~68 kDa protein. Transcriptional activator that binds to regulatory elements in promoter regions in a cell- and response element (target)-specific manner. Induces gene expression by binding as monomers to the NR4A1 response element (NBRE) 5'-AAAAGGTCA-3' site and as homodimers to the Nur response element (NurRE) site in the promoter of their regulated target genes. Plays a role in the regulation of proliferation, survival and differentiation of many different cell types and also in metabolism and inflammation. Mediates proliferation of vascular smooth muscle, myeloid progenitor cell and type B pancreatic cells; promotes mitogen-induced vascular smooth muscle cell proliferation through transactivation of SKP2 promoter by binding a NBRE site. Upon PDGF stimulation, stimulates vascular smooth muscle cell proliferation by regulating CCND1 and CCND2 expression. 1. Zhao, Y. et al. (2010) Circulation research 107, 501-11. PMID: 20558821 2. Liu, Q. et al. (2013) American journal of physiology. Endocrinology and metabolism 305, E1081-92. PMID: 24022864
Примечание	For research use only

Изображения

Ссылки

Даташит

Human NR4A3 Recombinant Protein (N-His).pdf

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Formula

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C₁ (Stock Conc.)

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Working Solution

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