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| カタログ番号 | HD793012 |
|---|---|
| 説明 |
Recombinant Human NT5C2 Protein, N-His (HD793012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | P49902 |
| タンパク質長 | Leu41-Ser474 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | Cytosolic 5'-nucleotidase II, Cytosolic IMP/GMP-specific 5'-nucleotidase, Cytosolic nucleoside phosphotransferase 5'N, Cytosolic purine 5'-nucleotidase, EC:2.7.1.77, EC:3.1.3.5, EC:3.1.3.99, High Km 5'-nucleotidase, NT5B, NT5C2, NT5CP, PNT5, cN-II |
| 背景 | Cytosolic purine 5'-nucleotidase is a ~64 kDa protein. Broad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates. In addition, possesses a phosphotransferase activity by which it can transfer a phosphate from a donor nucleoside monophosphate to an acceptor nucleoside, preferably inosine, deoxyinosine and guanosine. Has the highest activities for IMP and GMP followed by dIMP, dGMP and XMP. Could also catalyze the transfer of phosphates from pyrimidine monophosphates but with lower efficiency. Through these activities regulates the purine nucleoside/nucleotide pools within the cell. 1. Spychala, J. et al. (1999) European journal of biochemistry 259, 851-8. PMID: 10092873 2. Mazzon, C. et al. (2003) Biochemical pharmacology 66, 471-9. PMID: 12907246 3. Tozzi, MG. et al. (1991) Archives of biochemistry and biophysics 291, 212-7. PMID: 1659319 4. Allegrini, S. et al. (1997) The Biochemical journal 328 ( Pt 2), 483-7. PMID: 9371705 |
| 注意事項 | For research use only |
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