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| カタログ番号 | HC721012 |
|---|---|
| 説明 |
Recombinant Human NUF2 Protein, N-His (HC721012) expressed in E. coli, spanning Met1-Ser171. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q9BZD4 |
| タンパク質長 | Met1-Ser171 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 22.24 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | CDCA1, Cell division cycle-associated protein 1, Kinetochore protein Nuf2, NUF2, NUF2R, hNuf2, hNuf2R, hsNuf2 |
| 背景 | Kinetochore protein Nuf2 is a ~54 kDa protein. Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. 1. DeLuca, JG. et al. (2002) The Journal of cell biology 159, 549-55. PMID: 12438418 2. DeLuca, JG. et al. (2003) Current biology : CB 13, 2103-9. PMID: 14654001 3. Joseph, J. et al. (2004) Current biology : CB 14, 611-7. PMID: 15062103 4. Stucke, VM. et al. (2004) Chromosoma 113, 1-15. PMID: 15235793 5. Meraldi, P. et al. (2004) Developmental cell 7, 45-60. PMID: 15239953 6. DeLuca, JG. et al. (2005) Molecular biology of the cell 16, 519-31. PMID: 15548592 7. Liu, D. et al. (2007) The Journal of biological chemistry 282, 21415-24. PMID: 17535814 8. Schmidt, JC. et al. (2012) Developmental cell 23, 968-80. PMID: 23085020 |
| 注意事項 | For research use only |
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