

| Каталожный номер | HC721012 |
|---|---|
| Описание |
Recombinant Human NUF2 Protein, N-His (HC721012) expressed in E. coli, spanning Met1-Ser171. Purity: >90% by SDS-PAGE.
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | Q9BZD4 |
| Длина белка | Met1-Ser171 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Прогнозируемая молекулярная масса | 22.24 kDa |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | CDCA1, Cell division cycle-associated protein 1, Kinetochore protein Nuf2, NUF2, NUF2R, hNuf2, hNuf2R, hsNuf2 |
| Фон | Kinetochore protein Nuf2 is a ~54 kDa protein. Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. 1. DeLuca, JG. et al. (2002) The Journal of cell biology 159, 549-55. PMID: 12438418 2. DeLuca, JG. et al. (2003) Current biology : CB 13, 2103-9. PMID: 14654001 3. Joseph, J. et al. (2004) Current biology : CB 14, 611-7. PMID: 15062103 4. Stucke, VM. et al. (2004) Chromosoma 113, 1-15. PMID: 15235793 5. Meraldi, P. et al. (2004) Developmental cell 7, 45-60. PMID: 15239953 6. DeLuca, JG. et al. (2005) Molecular biology of the cell 16, 519-31. PMID: 15548592 7. Liu, D. et al. (2007) The Journal of biological chemistry 282, 21415-24. PMID: 17535814 8. Schmidt, JC. et al. (2012) Developmental cell 23, 968-80. PMID: 23085020 |
| Примечание | For research use only |
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