Human PAQR3 Recombinant Protein (N-His-KSI) (HD352012)

Name: Human PAQR3 Recombinant Protein (N-His-KSI)
Brand: abinScience
SKU: HD352012
Price: 211 USD
Availability: InStock

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50ug
100ug
1mg

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Обзор

Каталожный номер	HD352012
Описание	Recombinant Human PAQR3 Protein, N-His-KSI (HD352012) expressed in E. coli, spanning His2-Trp74. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q6TCH7
Длина белка	His2-Trp74
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	24.37 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	PAQR3, Progestin and adipoQ receptor family member 3, Progestin and adipoQ receptor family member III, RKTG, Raf kinase trapping to Golgi
Фон	Progestin and adipoQ receptor family member 3 is a ~36 kDa protein. Golgi-scaffold protein which modulates its interactors acitivies by anchoring them to the Golgi apparatus. Functions as a spatial regulator of RAF1 kinase by sequestrating it to the Golgi apparatus. Acts as a positive regulator of cholesterol biosynthesis by mediating the anchoring of the SCAP:SREBP complex in the Golgi apparatus, thereby promoting SCAP:SREBF2 complex formation, potentiating SREBF2 and SREBF1 processing and enhancing lipid synthesis. Also regulates PPARA and PPARG functions by mediating their interaction with E3 ubiquitin ligases, such as STUB1 or HUWE1, leading to their polyubiquitination and proteasome-mediated degradation. 1. Luo, X. et al. (2008) The Biochemical journal 414, 399-406. PMID: 18547165 2. Xu, D. et al. (2015) Nature communications 6, 8100. PMID: 26311497
Примечание	For research use only

Изображения

Ссылки

Даташит

Human PAQR3 Recombinant Protein (N-His-KSI).pdf

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Formula

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C₁ (Stock Conc.)

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Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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