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Human PARD3 Recombinant Protein (N-His) (HC188022)

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Vista general
Número de catálogoHC188022
Descripción
Recombinant Human PARD3 Protein, N-His (HC188022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresiónE. coli
Número de accesoQ8TEW0
Longitud de proteínaMet1-Glu81&Thr583-Arg683
AplicacionesELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspeciesHomo sapiens (Human)
Naturaleza Recombinant
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Forma Lyophilized
Buffer de almacenamiento Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosASIP, Atypical PKC isotype-specific-interacting protein, CTCL tumor antigen se2-5, PAR-3, PAR3, PAR3-alpha, PAR3A, PARD-3, PARD3, Partitioning defective 3 homolog
Fondo

Partitioning defective 3 homolog is a ~151 kDa protein. Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly.

1. Johansson, A. et al. (2000) Journal of cell science 113 ( Pt 18), 3267-75. PMID: 10954424
2. Chen, X. et al. (2017) Human mutation 38, 378-389. PMID: 27925688
3. Joberty, G. et al. (2000) Nature cell biology 2, 531-9. PMID: 10934474
4. Khazaei, MR. et al. (2009) The Journal of biological chemistry 284, 33571-9. PMID: 19812038
Nota For research use only
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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