

| Numéro de catalogue | HD424012 |
|---|---|
| Description |
Recombinant Human PARD6A Protein, N-His (HD424012) expressed in E. coli, spanning His161-Asn254. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q9NPB6 |
| Longueur de protéine | His161-Asn254 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 12.44 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | PAR-6, PAR-6 alpha, PAR-6A, PAR6A, PAR6C, PARD6A, Partitioning defective 6 homolog alpha, TIP-40, Tax interaction protein 40 |
| Contexte | Partitioning defective 6 homolog alpha is a ~37 kDa protein. Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Regulates centrosome organization and function. 1. Qiu, RG. et al. (2000) Current biology : CB 10, 697-707. PMID: 10873802 2. Kodani, A. et al. (2010) Molecular biology of the cell 21, 3376-85. PMID: 20719959 |
| Note | For research use only |
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