Human PEX1 Recombinant Protein (N-His) (HT197022)

Name: Human PEX1 Recombinant Protein (N-His)
Brand: abinScience
SKU: HT197022
Price: 211 USD
Availability: InStock

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Numéro de catalogue	HT197022
Description	Recombinant Human PEX1 Protein, N-His (HT197022) expressed in E. coli, spanning Ala15-Ile177. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	O43933
Longueur de protéine	Ala15-Ile177
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	20.68 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	EC:3.6.4.-, PEX1, Peroxin-1, Peroxisomal ATPase PEX1, Peroxisome biogenesis disorder protein 1, Peroxisome biogenesis factor 1
Contexte	Peroxisomal ATPase PEX1 is a ~142 kDa protein. Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling. Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel. Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5. 1. Tamura, S. et al. (2001) The Biochemical journal 357, 417-26. PMID: 11439091 2. Miyata, N. et al. (2005) Molecular and cellular biology 25, 10822-32. PMID: 16314507 3. Tamura, S. et al. (2006) The Journal of biological chemistry 281, 27693-704. PMID: 16854980 4. Nashiro, C. et al. (2011) Traffic (Copenhagen, Denmark) 12, 774-88. PMID: 21362118 5. Pedrosa, AG. et al. (2018) The Journal of biological chemistry 293, 11553-11563. PMID: 29884772
Note	For research use only

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Human PEX1 Recombinant Protein (N-His).pdf

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