Human PLXNB2 Recombinant Protein (N-His) (HC792012)

Name: Human PLXNB2 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC792012
Price: 211 USD
Availability: InStock

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Número de catálogo	HC792012
Descripción	Recombinant Human PLXNB2 Protein, N-His (HC792012) expressed in E. coli, spanning Gln56-Gly225. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	O15031
Longitud de proteína	Gln56-Gly225
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	20.74 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	KIAA0315, MM1, PLXNB2, Plexin-B2
Fondo	Plexin-B2 is a ~205 kDa protein. Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Plays a role in glutamatergic synapse development and is required for SEMA4A-mediated excitatory synapse development. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Also acts as a cell surface receptor for angiogenin (ANG); promoting ANG endocytosis and translocation to the cytoplasm or nucleus. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. 1. Yu, W. et al. (2017) Cell 171, 849-864.e25. PMID: 29100074 2. Bai, R. et al. (2020) The EMBO journal 39, e103325. PMID: 32510170 3. Perrot, V. et al. (2002) The Journal of biological chemistry 277, 43115-20. PMID: 12183458 4. Conrotto, P. et al. (2004) Oncogene 23, 5131-7. PMID: 15184888
Nota	For research use only

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Datasheet

Human PLXNB2 Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Working Solution

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