Human PLXNB2 Recombinant Protein (N-His) (HC792012)

Name: Human PLXNB2 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC792012
Price: 211 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HC792012
Description	Recombinant Human PLXNB2 Protein, N-His (HC792012) expressed in E. coli, spanning Gln56-Gly225. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	O15031
Longueur de protéine	Gln56-Gly225
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	20.74 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	KIAA0315, MM1, PLXNB2, Plexin-B2
Contexte	Plexin-B2 is a ~205 kDa protein. Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Plays a role in glutamatergic synapse development and is required for SEMA4A-mediated excitatory synapse development. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Also acts as a cell surface receptor for angiogenin (ANG); promoting ANG endocytosis and translocation to the cytoplasm or nucleus. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. 1. Yu, W. et al. (2017) Cell 171, 849-864.e25. PMID: 29100074 2. Bai, R. et al. (2020) The EMBO journal 39, e103325. PMID: 32510170 3. Perrot, V. et al. (2002) The Journal of biological chemistry 277, 43115-20. PMID: 12183458 4. Conrotto, P. et al. (2004) Oncogene 23, 5131-7. PMID: 15184888
Note	For research use only

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Human PLXNB2 Recombinant Protein (N-His).pdf

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