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| カタログ番号 | HD886012 |
|---|---|
| 説明 |
Recombinant Human POGLUT2 Protein, N-His (HD886012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q6UW63 |
| タンパク質長 | Ser32-Val468 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | EC:2.4.1.-, EC:2.4.2.-, EP58, ER protein 58, ERp58, Endoplasmic reticulum resident protein 58, KDEL motif-containing protein 1, KDELC1, POGLUT2, Protein O-glucosyltransferase 2, Protein O-xylosyltransferase POGLUT2 |
| 背景 | Protein O-glucosyltransferase 2 is a ~58 kDa protein. Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C. Can also catalyze the transfer of xylose from UDP-xylose but less efficiently. Specifically targets extracellular EGF repeats of proteins such as NOTCH1, NOTCH3, FBN1, FBN2 and LTBP1. May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway. 1. Takeuchi, H. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, E8395-E8402. PMID: 30127001 2. Williamson, DB. et al. (2021) The Journal of biological chemistry 297, 101055. PMID: 34411563 |
| 注意事項 | For research use only |
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