Human POU4F2 Recombinant Protein (N-His) (HC274022)

Name: Human POU4F2 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC274022
Price: 211 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HC274022
Description	Recombinant Human POU4F2 Protein, N-His (HC274022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Système d'expression	E. coli
Numéro d'accès	Q12837
Longueur de protéine	Ser243-Ile409
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	BRN3B, Brain-3B, Brain-specific homeobox/POU domain protein 3B, Brn-3B, POU domain, class 4, transcription factor 2, POU4F2
Contexte	POU domain, class 4, transcription factor 2 is a ~43 kDa protein. Tissue-specific DNA-binding transcription factor involved in the development and differentiation of target cells. Functions either as activator or repressor modulating the rate of target gene transcription through RNA polymerase II enzyme in a promoter-dependent manner. Binds to the consensus octamer motif 5'-AT[A/T]A[T/A]T[A/T]A-3' of promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Binds to an octamer site to form a ternary complex with ISL1; cooperates positively with ISL1 and ISL2 to potentiate transcriptional activation of RGC target genes being involved in RGC fate commitment in the developing retina and RGC axon formation and pathfinding. 1. Salichs, E. et al. (2009) PLoS genetics 5, e1000397. PMID: 19266028 2. Zhang, L. et al. (2013) Molecular vision 19, 1371-86. PMID: 23805044
Note	For research use only

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Human POU4F2 Recombinant Protein (N-His).pdf

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