Human PRKACB Recombinant Protein (N-His) (HD981012)

Name: Human PRKACB Recombinant Protein (N-His)
Brand: abinScience
SKU: HD981012
Price: 211 USD
Availability: InStock

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1mg

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Vista general

Número de catálogo	HD981012
Descripción	Recombinant Human PRKACB Protein, N-His (HD981012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P22694
Longitud de proteína	Met1-Phe351
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	EC:2.7.11.11, PKA C-beta, PRKACB, cAMP-dependent protein kinase catalytic subunit beta
Fondo	cAMP-dependent protein kinase catalytic subunit beta is a ~40 kDa protein. Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates GPKOW which regulates its ability to bind RNA. Acts as a negative regulator of mTORC1 by mediating phosphorylation of RPTOR. 1. Wu, KJ. et al. (2002) Oncogene 21, 7872-82. PMID: 12420224 2. Lignitto, L. et al. (2011) Nature cell biology 13, 412-22. PMID: 21423175 3. Jewell, JL. et al. (2019) eLife 8. PMID: 31112131 4. Aksaas, AK. et al. (2011) Journal of molecular signaling 6, 10. PMID: 21880142
Nota	For research use only

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Datasheet

Human PRKACB Recombinant Protein (N-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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