Human RAB35 Recombinant Protein (N-His) (HC165012)

Name: Human RAB35 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC165012
Price: 211 USD
Availability: InStock

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Número de catálogo	HC165012
Descripción	Recombinant Human RAB35 Protein, N-His (HC165012) expressed in E. coli, spanning Met1-Lys178. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q15286
Longitud de proteína	Met1-Lys178
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	22.42 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	EC:3.6.5.2, GTP-binding protein RAY, RAB1C, RAB35, RAY, Ras-related protein Rab-1C, Ras-related protein Rab-35
Fondo	Ras-related protein Rab-35 is a ~23 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB35 is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth. 1. Lin, L. et al. (2019) Structure (London, England : 1993) 27, 729-740.e3. PMID: 30905672 2. Rahajeng, J. et al. (2012) Traffic (Copenhagen, Denmark) 13, 82-93. PMID: 21951725 3. Kouranti, I. et al. (2006) Current biology : CB 16, 1719-25. PMID: 16950109
Nota	For research use only

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Datasheet

Human RAB35 Recombinant Protein (N-His).pdf

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