Human RAB35 Recombinant Protein (N-His) (HC165012)

Name: Human RAB35 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC165012
Price: 211 USD
Availability: InStock

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1mg

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Каталожный номер	HC165012
Описание	Recombinant Human RAB35 Protein, N-His (HC165012) expressed in E. coli, spanning Met1-Lys178. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q15286
Длина белка	Met1-Lys178
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	22.42 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	EC:3.6.5.2, GTP-binding protein RAY, RAB1C, RAB35, RAY, Ras-related protein Rab-1C, Ras-related protein Rab-35
Фон	Ras-related protein Rab-35 is a ~23 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB35 is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth. 1. Lin, L. et al. (2019) Structure (London, England : 1993) 27, 729-740.e3. PMID: 30905672 2. Rahajeng, J. et al. (2012) Traffic (Copenhagen, Denmark) 13, 82-93. PMID: 21951725 3. Kouranti, I. et al. (2006) Current biology : CB 16, 1719-25. PMID: 16950109
Примечание	For research use only

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Даташит

Human RAB35 Recombinant Protein (N-His).pdf

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