Human RABGGTB Recombinant Protein (N-His) (HD068012)

Name: Human RABGGTB Recombinant Protein (N-His)
Brand: abinScience
SKU: HD068012
Price: 211 USD
Availability: InStock

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1mg

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Каталожный номер	HD068012
Описание	Recombinant Human RABGGTB Protein, N-His (HD068012) expressed in E. coli, spanning Glu21-Ser331. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	P53611
Длина белка	Glu21-Ser331
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Прогнозируемая молекулярная масса	37.08 kDa
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	EC:2.5.1.60, GGTB, GGTase-II-beta, Geranylgeranyl transferase type II subunit beta, Geranylgeranyl transferase type-2 subunit beta, RABGGTB, Rab GG transferase beta, Rab GGTase beta, Rab geranyl-geranyltransferase subunit beta, Rab geranylgeranyltransferase subunit beta, Type II protein geranyl-geranyltransferase subunit beta
Фон	Geranylgeranyl transferase type-2 subunit beta is a ~36 kDa protein. Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A. Catalytic subunit of the geranylgeranyl transferase type 3 (GGTase-3) complex. The GGTase-3 complex geranylgeranylates and targets FBXL2 to the cellular membranes, where FBXL2 forms part of the E3 ubiquitin-protein ligase complex SCF(FBXL2) that mediates the degradation of membrane-anchored proteins. The GGTase-3 complex geranylgeranylates Golgi v-SNARE protein YKT6 at 'Cys-194' and this prenylation is required for Golgi SNARE complex assembly. 1. Farnsworth, CC. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 11963-7. PMID: 7991565 2. Kuchay, S. et al. (2019) Nature structural & molecular biology 26, 628-636. PMID: 31209342 3. Shirakawa, R. et al. (2020) The EMBO journal 39, e104120. PMID: 32128853
Примечание	For research use only

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Human RABGGTB Recombinant Protein (N-His).pdf

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