

| Numéro de catalogue | HD034012 |
|---|---|
| Description |
Recombinant Human RANBP1 Protein, N-His (HD034012) expressed in E. coli, spanning Asp44-Gln201. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | P43487 |
| Longueur de protéine | Asp44-Gln201 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 20.74 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | RANBP1, Ran-binding protein 1, Ran-specific GTPase-activating protein, RanBP1 |
| Contexte | Ran-specific GTPase-activating protein is a ~23 kDa protein. Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus. Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins. Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L. 1. Koyama, M. et al. (2010) The EMBO journal 29, 2002-13. PMID: 20485264 2. Li, HY. et al. (2007) Cell cycle (Georgetown, Tex.) 6, 1886-95. PMID: 17671426 3. Bischoff, FR. et al. (1995) The EMBO journal 14, 705-15. PMID: 7882974 4. Hayashi, N. et al. (1995) Molecular & general genetics : MGG 247, 661-9. PMID: 7616957 |
| Note | For research use only |
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