

| Número de catálogo | HD937012 |
|---|---|
| Descripción |
Recombinant Human RBL1 Protein, N-His (HD937012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Sistema de expresión | E. coli |
| Número de acceso | P28749 |
| Longitud de proteína | Thr391-Ser581 |
| Aplicaciones | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Especies | Homo sapiens (Human) |
| Naturaleza | Recombinant |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >90% as determined by SDS-PAGE. |
| Forma | Lyophilized |
| Buffer de almacenamiento | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | 107 kDa retinoblastoma-associated protein, RBL1, Retinoblastoma-like protein 1, p107, pRb1 |
| Fondo | Retinoblastoma-like protein 1 is a ~120 kDa protein. Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. 1. Schmit, F. et al. (2007) Cell cycle (Georgetown, Tex.) 6, 1903-13. PMID: 17671431 2. Zhu, L. et al. (1993) Genes & development 7, 1111-25. PMID: 8319904 |
| Nota | For research use only |
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