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| カタログ番号 | HC868012 |
|---|---|
| 説明 |
Recombinant Human RBM47 Protein, N-His (HC868012) expressed in E. coli, spanning Asn31-Gly334. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | A0AV96 |
| タンパク質長 | Asn31-Gly334 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 36.94 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | RBM47, RNA-binding motif protein 47, RNA-binding protein 47 |
| 背景 | RNA-binding protein 47 is a ~64 kDa protein. Single-stranded RNA-binding protein that functions in a variety of RNA processes, including alternative splicing, RNA stabilization, and RNA editing. Functions as an enzyme-substrate adapter for the cytidine deaminase APOBEC1. With APOBEC1 forms an mRNA editing complex involved into cytidine to uridine editing of a variety of mRNA molecules. Through the binding of their 3'UTR, also stabilizes a variety of mRNAs and regulates the expression of genes such as the interferon alpha/beta receptor and interleukin-10. Also involved in the alternative splicing of several genes including TJP1. 1. Guan, R. et al. (2013) Developmental dynamics : an official publication of the American Association of Anatomists 242, 1395-404. PMID: 24038582 2. Fossat, N. et al. (2014) EMBO reports 15, 903-10. PMID: 24916387 3. Cieply, B. et al. (2016) Cell reports 15, 247-55. PMID: 27050523 4. Wolfe, AD. et al. (2019) Journal of molecular biology 431, 1506-1517. PMID: 30844405 5. Kim, YE. et al. (2019) Oncogene 38, 6521-6536. PMID: 31358901 6. Wang, K. et al. (2021) EMBO reports 22, e52205. PMID: 34160127 |
| 注意事項 | For research use only |
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