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| カタログ番号 | HC958012 |
|---|---|
| 説明 |
Recombinant Human RDH16 Protein, N-His (HC958012) expressed in E. coli, spanning Arg28-Lys288. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | O75452 |
| タンパク質長 | Arg28-Lys288 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 31.21 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | EC:1.1.1.105, EC:1.1.1.209, EC:1.1.1.315, EC:1.1.1.53, Human epidermal retinol dehydrogenase, Microsomal NAD(+)-dependent retinol dehydrogenase 4, RDH16, RODH4, Retinol dehydrogenase 16, RoDH-4, SDR9C8, Short chain dehydrogenase/reductase family 9C member 8, Sterol/retinol dehydrogenase, hRDH-E |
| 背景 | Retinol dehydrogenase 16 is a ~35 kDa protein. Oxidoreductase with a preference for NAD. Oxidizes all-trans-retinol, 9-cis-retinol, 11-cis-retinol and 13-cis-retinol to the corresponding aldehydes. Has higher activity towards CRBP-bound retinol than with free retinol. Also oxidizes 3-alpha-hydroxysteroids. Oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione. 1. Jurukovski, V. et al. (1999) Molecular genetics and metabolism 67, 62-73. PMID: 10329026 2. Lapshina, EA. et al. (2003) Biochemistry 42, 776-84. PMID: 12534290 3. Gough, WH. et al. (1998) The Journal of biological chemistry 273, 19778-85. PMID: 9677409 4. Fiandalo, MV. et al. (2018) Oncotarget 9, 11227-11242. PMID: 29541409 |
| 注意事項 | For research use only |
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