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| カタログ番号 | HD339011 |
|---|---|
| 説明 |
Recombinant Human RNASE6 Protein, C-His (HD339011) expressed in Yeast Cells, spanning Trp24-Leu150. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | Yeast cells |
| アクセッション番号 | Q93091 |
| タンパク質長 | Trp24-Leu150 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 15.97 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | EC:3.1.27.-, RNASE6, RNS6, RNase K6, Ribonuclease K6 |
| 背景 | Ribonuclease K6 is a ~17 kDa protein. Ribonuclease which shows a preference for the pyrimidines uridine and cytosine. Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including P.aeruginosa, A.baumanii, M.luteus, S.aureus, E.faecalis, E.faecium, S.saprophyticus and E.coli. Causes loss of bacterial membrane integrity, and also promotes agglutination of Gram-negative bacteria. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. 1. Prats-Ejarque, G. et al. (2016) The Biochemical journal 473, 1523-36. PMID: 27013146 2. Rosenberg, HF. et al. (1996) Nucleic acids research 24, 3507-13. PMID: 8836175 3. Becknell, B. et al. (2015) Kidney international 87, 151-61. PMID: 25075772 4. Pulido, D. et al. (2016) International journal of molecular sciences 17, 552. PMID: 27089320 |
| 注意事項 | For research use only |
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