

| Numéro de catalogue | HC738012 |
|---|---|
| Description |
Recombinant Human SART3 Protein, N-His (HC738012) expressed in E. coli, spanning Asp111-Ser558. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q15020 |
| Longueur de protéine | Asp111-Ser558 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 55.08 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | KIAA0156, SART-3, SART3, Spliceosome associated factor 3, U4/U6 recycling protein, Squamous cell carcinoma antigen recognized by T-cells 3, TIP110, Tat-interacting protein of 110 kDa, Tip110, p110 nuclear RNA-binding protein |
| Contexte | Spliceosome associated factor 3, U4/U6 recycling protein is a ~109 kDa protein. U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation. Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites. May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. 1. Bell, M. et al. (2002) The EMBO journal 21, 2724-35. PMID: 12032085 2. Damianov, A. et al. (2004) Molecular and cellular biology 24, 1700-8. PMID: 14749385 3. Song, EJ. et al. (2010) Genes & development 24, 1434-47. PMID: 20595234 4. Long, L. et al. (2014) The Journal of biological chemistry 289, 8916-30. PMID: 24526689 |
| Note | For research use only |
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