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| カタログ番号 | HC738012 |
|---|---|
| 説明 |
Recombinant Human SART3 Protein, N-His (HC738012) expressed in E. coli, spanning Asp111-Ser558. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q15020 |
| タンパク質長 | Asp111-Ser558 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 55.08 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | KIAA0156, SART-3, SART3, Spliceosome associated factor 3, U4/U6 recycling protein, Squamous cell carcinoma antigen recognized by T-cells 3, TIP110, Tat-interacting protein of 110 kDa, Tip110, p110 nuclear RNA-binding protein |
| 背景 | Spliceosome associated factor 3, U4/U6 recycling protein is a ~109 kDa protein. U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation. Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites. May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. 1. Bell, M. et al. (2002) The EMBO journal 21, 2724-35. PMID: 12032085 2. Damianov, A. et al. (2004) Molecular and cellular biology 24, 1700-8. PMID: 14749385 3. Song, EJ. et al. (2010) Genes & development 24, 1434-47. PMID: 20595234 4. Long, L. et al. (2014) The Journal of biological chemistry 289, 8916-30. PMID: 24526689 |
| 注意事項 | For research use only |
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