Human SCN1B Recombinant Protein (N-His) (HD851012)

Name: Human SCN1B Recombinant Protein (N-His)
Brand: abinScience
SKU: HD851012
Price: 211 USD
Availability: InStock

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Número de catálogo	HD851012
Descripción	Recombinant Human SCN1B Protein, N-His (HD851012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q07699
Longitud de proteína	Gly19-Lys149
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	SCN1B, Sodium channel regulatory subunit beta-1
Fondo	Sodium channel regulatory subunit beta-1 is a ~24 kDa protein. Regulatory subunit of multiple voltage-gated sodium (Nav) channels directly mediating the depolarization of excitable membranes. Navs, also called VGSCs (voltage-gated sodium channels) or VDSCs (voltage-dependent sodium channels), operate by switching between closed and open conformations depending on the voltage difference across the membrane. In the open conformation they allow Na(+) ions to selectively pass through the pore, along their electrochemical gradient. The influx of Na+ ions provokes membrane depolarization, initiating the propagation of electrical signals throughout cells and tissues. The accessory beta subunits participate in localization and functional modulation of the Nav channels. 1. Qin, N. et al. (2003) European journal of biochemistry 270, 4762-70. PMID: 14622265 2. Spampanato, J. et al. (2004) The Journal of neuroscience : the official journal of the Society for Neuroscience 24, 10022-34. PMID: 15525788 3. Watanabe, H. et al. (2008) The Journal of clinical investigation 118, 2260-8. PMID: 18464934 4. Patino, GA. et al. (2009) The Journal of neuroscience : the official journal of the Society for Neuroscience 29, 10764-78. PMID: 19710327 5. Baroni, D. et al. (2018) Human mutation 39, 1402-1415. PMID: 29992740 6. Fan, X. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2220578120. PMID: 36696443 7. Makita, N. et al. (1994) The Journal of biological chemistry 269, 7571-8. PMID: 8125980 8. McClatchey, AI. et al. (1993) Human molecular genetics 2, 745-9. PMID: 8394762 9. Shen, H. et al. (2019) Science (New York, N.Y.) 363, 1303-1308. PMID: 30765606
Nota	For research use only

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Datasheet

Human SCN1B Recombinant Protein (N-His).pdf

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Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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