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Обзор
Каталожный номерHD952012
Описание
Recombinant Human SCNN1B Protein, N-His (HD952012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
Система экспрессииE. coli
Номер доступаP51168
Длина белкаSer76-Ala512
ПримененияELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
ВидыHomo sapiens (Human)
Характер Recombinant
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >90% as determined by SDS-PAGE.
Форма Lyophilized
Буфер хранения Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Реконституция Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названияAmiloride-sensitive sodium channel subunit beta, Beta-ENaC, Beta-NaCH, ENaC subunit beta, ENaCB, Epithelial Na(+) channel subunit beta, Epithelial sodium channel subunit beta, Nonvoltage-gated sodium channel 1 subunit beta, SCNEB, SCNN1B
Фон

Epithelial sodium channel subunit beta is a ~72 kDa protein. This is one of the three pore-forming subunits of the heterotrimeric epithelial sodium channel (ENaC), a critical regulator of sodium balance and fluid homeostasis. ENaC operates in epithelial tissues, where it mediates the electrodiffusion of sodium ions from extracellular fluid through the apical membrane of cells, with water following osmotically. It plays a key role in maintaining sodium homeostasis through electrogenic sodium reabsorption in the kidneys. Additionally, ENaC is essential for airway surface liquid homeostasis, which is crucial for proper mucus clearance.

1. Noreng, S. et al. (2018) eLife 7. PMID: 30251954
2. Noreng, S. et al. (2020) eLife 9. PMID: 32729833
3. McDonald, FJ. et al. (1995) The American journal of physiology 268, C1157-63. PMID: 7762608
4. Goulet, CC. et al. (1998) The Journal of biological chemistry 273, 30012-7. PMID: 9792722
5. Hobbs, CA. et al. (2013) American journal of physiology. Lung cellular and molecular physiology 305, L990-L1001. PMID: 24124190
6. Saxena, A. et al. (2002) The Journal of clinical endocrinology and metabolism 87, 3344-50. PMID: 12107247
Примечание For research use only
Изображения
Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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