

| Каталожный номер | HD658012 |
|---|---|
| Описание |
Recombinant Human SCNN1D Protein, N-His (HD658012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | P51172 |
| Длина белка | Arg277-Tyr683 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | Amiloride-sensitive sodium channel subunit delta, DNACH, Delta-ENaC, Delta-NaCH, ENaCD, Epithelial Na(+) channel subunit delta, Epithelial sodium channel subunit delta, Nonvoltage-gated sodium channel 1 subunit delta, SCNED, SCNN1D |
| Фон | Epithelial sodium channel subunit delta is a ~87 kDa protein. Potential alternative pore-forming subunit of the epithelial sodium channel (ENaC), capable of replacing the alpha/SCNN1A subunit, creating a more active channel with distinct properties. ENaC functions in epithelial tissues, where it facilitates the electrodiffusion of sodium ions from the extracellular fluid through the apical membrane of cells, with water following osmotically, regulating sodium balance and fluid homeostasis. This subunit could also function independently as a sodium channel or assemble into other tissue-specific heterotrimeric sodium channels. 1. Ji, HL. et al. (2006) The Journal of biological chemistry 281, 8233-41. PMID: 16423824 2. Bangel-Ruland, N. et al. (2010) American journal of respiratory cell and molecular biology 42, 498-505. PMID: 19520916 3. Zhao, RZ. et al. (2012) American journal of physiology. Lung cellular and molecular physiology 302, L1262-72. PMID: 22505667 4. Waldmann, R. et al. (1995) The Journal of biological chemistry 270, 27411-4. PMID: 7499195 |
| Примечание | For research use only |
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