Human SEC61B Recombinant Protein (N-GST & C-His) (HC176012)

Name: Human SEC61B Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HC176012
Price: 211 USD
Availability: InStock

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Número de catálogo	HC176012
Descripción	Recombinant Human SEC61B Protein, N-GST & C-His (HC176012) expressed in E. coli, spanning Glu61-Ser96. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P60468
Longitud de proteína	Glu61-Ser96
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	32.17 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	Protein transport protein Sec61 subunit beta, SEC61B
Fondo	Protein transport protein Sec61 subunit beta is a ~9 kDa protein. Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex. The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER. 1. Meacock, SL. et al. (2002) Molecular biology of the cell 13, 4114-29. PMID: 12475939 2. McGilvray, PT. et al. (2020) eLife 9. PMID: 32820719 3. Sundaram, A. et al. (2022) Nature 611, 167-172. PMID: 36261522 4. Oresic, K. et al. (2009) The Journal of biological chemistry 284, 5905-14. PMID: 19121997
Nota	For research use only

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Datasheet

Human SEC61B Recombinant Protein (N-GST & C-His).pdf

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