Human SEC63 Recombinant Protein (N-His) (HC742012)

Name: Human SEC63 Recombinant Protein (N-His)
Brand: abinScience
SKU: HC742012
Price: 211 USD
Availability: InStock

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Número de catálogo	HC742012
Descripción	Recombinant Human SEC63 Protein, N-His (HC742012) expressed in E. coli, spanning Arg226-Gly376. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	Q9UGP8
Longitud de proteína	Arg226-Gly376
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	19.76 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	DNAJC23, DnaJ homolog subfamily C member 23, SEC63, SEC63L, Translocation protein SEC63 homolog
Fondo	Translocation protein SEC63 homolog is a ~87 kDa protein. Mediates cotranslational and post-translational transport of certain precursor polypeptides across endoplasmic reticulum (ER). Proposed to play an auxiliary role in recognition of precursors with short and apolar signal peptides. May cooperate with SEC62 and HSPA5/BiP to facilitate targeting of small presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia. 1. Lang, S. et al. (2012) Journal of cell science 125, 1958-69. PMID: 22375059 2. Haßdenteufel, S. et al. (2018) Cell reports 23, 1373-1386. PMID: 29719251
Nota	For research use only

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Datasheet

Human SEC63 Recombinant Protein (N-His).pdf

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