Human SLC10A1 Recombinant Protein (N-GST & C-His) (HC429032)

Name: Human SLC10A1 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HC429032
Price: 211 USD
Availability: InStock

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100ug
1mg

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Каталожный номер	HC429032
Описание	Recombinant Human SLC10A1 Protein, N-GST & C-His (HC429032) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
Система экспрессии	E. coli
Номер доступа	Q14973
Длина белка	Phe244-Phe284
Применения	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Виды	Homo sapiens (Human)
Характер	Recombinant
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>90% as determined by SDS-PAGE.
Форма	Lyophilized
Буфер хранения	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Доставка	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	Cell growth-inhibiting gene 29 protein, Hepatic sodium/bile acid cotransporter, NTCP, Na(+)/bile acid cotransporter, Na(+)/taurocholate transport protein, SLC10A1, Sodium/taurocholate cotransporting polypeptide, Solute carrier family 10 member 1
Фон	Hepatic sodium/bile acid cotransporter is a ~38 kDa protein. As a major transporter of conjugated bile salts from plasma into the hepatocyte, it plays a key role in the enterohepatic circulation of bile salts necessary for the solubilization and absorption of dietary fat and fat-soluble vitamins. It is strictly dependent on the extracellular presence of sodium. It exhibits broad substrate specificity and transports various bile acids, such as taurocholate, cholate, as well as non-bile acid organic compounds, such as estrone sulfate. Works collaboratively with the ileal transporter (NTCP2), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation. 1. Ho, RH. et al. (2004) The Journal of biological chemistry 279, 7213-22. PMID: 14660639 2. Vaz, FM. et al. (2015) Hepatology (Baltimore, Md.) 61, 260-7. PMID: 24867799 3. Floerl, S. et al. (2021) SLAS discovery : advancing life sciences R & D 26, 1055-1064. PMID: 34060352 4. Hagenbuch, B. et al. (1994) The Journal of clinical investigation 93, 1326-31. PMID: 8132774 5. Kunst, RF. et al. (2021) Hepatology (Baltimore, Md.) 73, 2577-2585. PMID: 33222321
Примечание	For research use only