

| Numéro de catalogue | HW629022 |
|---|---|
| Description |
Recombinant Human SLC1A2 Protein, N-GST & C-His (HW629022) expressed in E. coli, spanning His143-Glu235. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | P43004 |
| Longueur de protéine | His143-Glu235 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 38.36 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | EAAT2, Excitatory amino acid transporter 2, GLT1, Glutamate/aspartate transporter II, SLC1A2, Sodium-dependent glutamate/aspartate transporter 2, Solute carrier family 1 member 2 |
| Contexte | Excitatory amino acid transporter 2 is a ~62 kDa protein. Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate. 1. Melzer, N. et al. (2003) The Journal of biological chemistry 278, 50112-9. PMID: 14506254 2. Gendreau, S. et al. (2004) The Journal of biological chemistry 279, 39505-12. PMID: 15265858 3. Abousaab, A. et al. (2016) The Journal of membrane biology 249, 239-49. PMID: 26690923 4. Arriza, JL. et al. (1994) The Journal of neuroscience : the official journal of the Society for Neuroscience 14, 5559-69. PMID: 7521911 |
| Note | For research use only |
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