

| Numéro de catalogue | HD846012 |
|---|---|
| Description |
Recombinant Human SLC25A11 Protein, N-His-KSI (HD846012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q02978 |
| Longueur de protéine | Ala140-Gly183 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 20.79 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | Alpha-oxoglutarate carrier, Mitochondrial 2-oxoglutarate/malate carrier protein, OGCP, SLC20A4, SLC25A11, Solute carrier family 25 member 11 |
| Contexte | Mitochondrial 2-oxoglutarate/malate carrier protein is a ~34 kDa protein. Catalyzes the transport of 2-oxoglutarate (alpha-oxoglutarate) across the inner mitochondrial membrane in an electroneutral exchange for malate. Can also exchange 2-oxoglutarate for other dicarboxylic acids such as malonate, succinate, maleate and oxaloacetate, although with lower affinity. Substrate exchange across the membrane occurs consecutively with one substrate being transported first, then dissociating from the substrate binding site before the second substrate binds for transport in the opposite direction. Does not transport glutathione. Contributes to several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, gluconeogenesis from lactate, and nitrogen metabolism. 1. Booty, LM. et al. (2015) FEBS letters 589, 621-8. PMID: 25637873 2. Cimadamore-Werthein, C. et al. (2024) The EMBO journal 43, 3450-3465. PMID: 38937634 3. Gallo, M. et al. (2011) PloS one 6, e17827. PMID: 21448454 |
| Note | For research use only |

SDS-PAGE for Human SLC25A11 Recombinant Protein (N-His-KSI)
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