

| Каталожный номер | HD846012 |
|---|---|
| Описание |
Recombinant Human SLC25A11 Protein, N-His-KSI (HD846012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | Q02978 |
| Длина белка | Ala140-Gly183 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Homo sapiens (Human) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Прогнозируемая молекулярная масса | 20.79 kDa |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | Alpha-oxoglutarate carrier, Mitochondrial 2-oxoglutarate/malate carrier protein, OGCP, SLC20A4, SLC25A11, Solute carrier family 25 member 11 |
| Фон | Mitochondrial 2-oxoglutarate/malate carrier protein is a ~34 kDa protein. Catalyzes the transport of 2-oxoglutarate (alpha-oxoglutarate) across the inner mitochondrial membrane in an electroneutral exchange for malate. Can also exchange 2-oxoglutarate for other dicarboxylic acids such as malonate, succinate, maleate and oxaloacetate, although with lower affinity. Substrate exchange across the membrane occurs consecutively with one substrate being transported first, then dissociating from the substrate binding site before the second substrate binds for transport in the opposite direction. Does not transport glutathione. Contributes to several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, gluconeogenesis from lactate, and nitrogen metabolism. 1. Booty, LM. et al. (2015) FEBS letters 589, 621-8. PMID: 25637873 2. Cimadamore-Werthein, C. et al. (2024) The EMBO journal 43, 3450-3465. PMID: 38937634 3. Gallo, M. et al. (2011) PloS one 6, e17827. PMID: 21448454 |
| Примечание | For research use only |

SDS-PAGE for Human SLC25A11 Recombinant Protein (N-His-KSI)
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