

| Numéro de catalogue | HD917012 |
|---|---|
| Description |
Recombinant Human SREBF2 Protein, N-His (HD917012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q12772 |
| Longueur de protéine | Arg569-Arg773 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | BHLHD2, Class D basic helix-loop-helix protein 2, Processed sterol regulatory element-binding protein 2, SREBF2, SREBP-2, SREBP2, Sterol regulatory element-binding protein 2, Sterol regulatory element-binding transcription factor 2, Transcription factor SREBF2, bHLHd2 |
| Contexte | Sterol regulatory element-binding protein 2 is a ~123 kDa protein. Precursor of the transcription factor form (Processed sterol regulatory element-binding protein 2), which is embedded in the endoplasmic reticulum membrane. Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis. 1. Xu, D. et al. (2020) Nature 580, 530-535. PMID: 32322062 |
| Note | For research use only |
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