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| カタログ番号 | HD917012 |
|---|---|
| 説明 |
Recombinant Human SREBF2 Protein, N-His (HD917012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q12772 |
| タンパク質長 | Arg569-Arg773 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | BHLHD2, Class D basic helix-loop-helix protein 2, Processed sterol regulatory element-binding protein 2, SREBF2, SREBP-2, SREBP2, Sterol regulatory element-binding protein 2, Sterol regulatory element-binding transcription factor 2, Transcription factor SREBF2, bHLHd2 |
| 背景 | Sterol regulatory element-binding protein 2 is a ~123 kDa protein. Precursor of the transcription factor form (Processed sterol regulatory element-binding protein 2), which is embedded in the endoplasmic reticulum membrane. Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis. 1. Xu, D. et al. (2020) Nature 580, 530-535. PMID: 32322062 |
| 注意事項 | For research use only |
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